Post by UCL Hawkes Institute

Tackling Alzheimer's disease and dementia is one of the biggest clinical priorities in the world today. To mark the end of World Alzheimer’s Month, we wrote an article summarising key research that is being conducted by Hawkes Institute researchers on this topic. Researchers at the MANIFOLD lab, led by Prof James Cole, have focused on developing automated machine learning to predict dementia risk and investigating how bias and trust in AI models can be improved. The team at our COMBINE lab, led by Prof Andre Altmann, has been using deep normative models to detect early brain changes associated with AD before the onset of dementia and to determine how genetic factors affect AD disease progression. Researchers in the POND group have been working on developing new computational methods used to identify patterns of disease progression in AD, with projects differentiating subtypes of AD pathology spread through the brain and homogenous groups of AD patients using predictive risk factors such as co-morbidities, physiological and lifestyle factors. Lastly, researchers at the Unit for Lifelong Health and Ageing at UCL (LHA) have been investigating the relationship between biomarkers of cerebral small vessel disease (CVSD) and Alzheimer onset and progression over time. Keen to find out more about these projects? Read our article at https://lnkd.in/dP5vEgDp James Cole Andre Altmann Daniel Alexander Geoff Parker Ellie Thompson Moona Mazher Carole Sudre Serena Verdi Francesca B. Sophie M. Maitrei Kohli Douglas Wyllie Alice Accorroni UCL Computer Science Unit for Lifelong Health and Ageing at UCL