Post by Tushar Babar

📢 OECD Releases Seven New Test Guidelines – A Major Milestone in Regulatory Toxicology & Ecotoxicology The OECD has introduced seven new Test Guidelines, further strengthening chemical safety assessment while supporting modern, science-based and animal-reduction approaches. New OECD Test Guidelines (2026): 🧬 OECD TG 255 – Bumblebee (Bombus spp.) Chronic Oral Toxicity Test (10-Day Feeding) 🪱 OECD TG 256 – Determination of Effects on Earthworms (Oligochaeta, Annelida) in Field Studies 🧪 OECD TG 445A – Determination of Cytochrome P450 (CYP) Induction using Differentiated Human Hepatic Cells 🧬 OECD TG 446A – ToxTracker Gene Reporter Assay for Identification of Genotoxic Hazard and Genotoxic/Non-Genotoxic Mechanisms of Action 🧫 OECD TG 454A – Human Glucocorticoid Receptor Transactivation Assay In addition, two important existing guidelines have been revised: 🔄 OECD TG 442C – In Chemico Skin Sensitisation (Updated) 🔄 OECD TG 442D – In Vitro Skin Sensitisation (Updated) These developments expand the toolbox for regulatory testing by improving the assessment of: 🐝 Pollinator protection 🌱 Terrestrial environmental risk 🧬 Genotoxicity ⚕️ Endocrine activity 💊 Drug metabolism 🧪 Non-animal testing approaches (NAMs) As an ecotoxicology professional, I am particularly excited to see the addition of new higher-tier terrestrial and pollinator guidelines, which will further strengthen environmental risk assessment and support global regulatory harmonization. #OECD #OECDTestGuidelines #Ecotoxicology #Toxicology #GLP #RegulatoryScience #EnvironmentalRiskAssessment #Pollinators #Earthworm #Bumblebee #Genotoxicity #NAMs #ChemicalSafety #StudyDirector #CRO