Post by Thermo Fisher Scientific

New Approach Methodologies, or NAMs, are human-relevant, non-animal approaches that are helping reshape how science evaluates safety and efficacy earlier in drug development. 3 things to know: 1. They can help change how drug development starts. New Approach Methodologies use tools like cell-based models, in chemico assays and computational modeling to help evaluate safety and efficacy earlier in development. 2. Momentum is growing. In 2025, the FDA and other regulatory bodies signaled stronger support for NAMs, including guidance that encourages developers to include NAM-derived data and a broader push to phase out animal testing for some programs. 3. They depend on rigorous science. Organoids, tumoroids and advanced analytical tools can help generate data that is more human-relevant, and Thermo Fisher is helping customers build and validate the workflows behind that shift. NAMs are not a short-term trend. They are part of a multi-year transformation toward more human-relevant research, with the potential to improve safety, reduce cost and help bring new therapies forward sooner. Learn more about the potential of NAMs in this Q&A with Thermo Fisher’s John Bishop: https://lnkd.in/dmbA6ZbJ