Post by Theraputo

45M on haloperidol, rigid, febrile 39.5°C, confused — what's the creatinine kinase? 📋 **Case:** A 45-year-old man with schizophrenia on haloperidol 10mg/day presents with fever (39.5°C), muscle rigidity, altered mental status, and autonomic instability. His serum CK is 45,000 IU/L. Which of the following is the BEST next step in management? **Options:** A. Increase haloperidol dose B. Start dantrolene + supportive care C. Start ECT immediately D. Switch to clozapine ✅ **Answer: B** 📖 **Explanation:** NMS is a medical emergency with ~10% mortality. First-line management includes: immediate withdrawal of antipsychotic, IV dantrolene (1-2.5 mg/kg) or bromocriptine, aggressive IV fluids for rhabdomyolysis, and supportive care in ICU. ECT is reserved for refractory cases. 💬 What would YOU do? Comment below Follow @theraputo for daily clinical content. #MCQ #PSYCHIATRY/EMERGENCY #WhatsYourDiagnosis #ClinicalPearls #MedTwitter #Theraputo #DoctorLife #MedStudent #AIIMS #PGIMER #KolkataDoctor #trending #explore #foryoupage