Post by Sofia Trampari

Interdisciplinary Scientist | Experimental Workflows & Cross-Functional Collaboration | Translating Complex Research into Actionable Outcomes

Structural biology is a field that is rising beyond the 'classic' macromolecular structural determination. But even in that case the new experimental approaches and technological advancements contribute to one main bottleneck: the data acquisition rates are rapidly outpacing our infrastructure for transfer, processing, and long-term storage. Beyond the massive volume of data, the recent workshop with the HDRMX consortium at the 2025 ACA meeting highlighted that metadata integrity is the true critical factor for the future of our field. Without rigorous, standardized metadata, the data risks becoming decontectualized, making long-term storage and scientific reproducibility increasingly difficult. The report of the HDRMX meeting of 2025 is now published here: https://lnkd.in/eT6wQX2U I am very glad to have been part of this report and community! Many thanks for the nice discussions to all the participants and authors: Christine Beavers, Herbert J. Bernstein, Aaron Brewster, Max Burian, @Nicholas Devenish, Jiaxin (Dawn) Duan, Daniel Ericsson, Diego Gaemperle, Yang Ha, Dave Hall, James Holton, Peter Keller, Loes Kroon-Batenburg, David Mittan-Moreau, PhD, @Yasukazu Nakaye, Daniel Paley, Ezra Peisach, Nicholas Sauter, Clemens Vonrhein, David Waterman, @Thomas White, Graeme Winter #Crystallography #SerialCrystallography #Metadata #HDRMX #ScientificComputing #StructuralBiology

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