Post by Sanford Burnham Prebys

Researchers at Sanford Burnham Prebys have uncovered an epigenetic mechanism that helps explain why some prostate cancers remain slow-growing while others become aggressive and spread. Led by Paul Boutros, PhD, MBA, the team analyzed more than 3,000 prostate tumor methylomes and identified four distinct DNA methylation patterns that closely predict how a patient's cancer is likely to behave. The findings could help clinicians better distinguish patients who need aggressive treatment from those who may be spared unnecessary therapies. Published in Cancer Discovery, the study also highlights the power of international collaboration, bringing together researchers from 22 institutions around the world. https://lnkd.in/gEAXPCvy