Post by Prinses Máxima Centrum voor kinderoncologie

After treatment for a brain tumor, 14-year-old Roan lives with acquired hypothalamic obesity. Damage to the hormone center means his brain no longer regulates hunger properly, leaving him with a constant feeling of hunger despite eating very little. The results of a clinical study, published today in the New England Journal of Medicine, show that setmelanotide can significantly lower BMI in children and adults with acquired hypothalamic obesity by restoring the brain's satiety signaling. Prof. Hanneke van Santen, pediatric endocrinologist at the Princess Máxima Center and WKZ, led the Dutch arm of this international study. She says: 'The effect of setmelanotide was remarkable, it gives children with hypothalamic obesity and their families new hope. Children who previously struggled with obesity and many other related problems truly seemed to come back to life. I hope we can soon offer setmelanotide to all children living with obesity caused by hypothalamic damage.' For children like Roan, the impact goes beyond weight. It means the possibility of living a life no longer dominated by constant hunger. Wilhelmina Kinderziekenhuis (WKZ), Rhythm Pharmaceuticals Inc., Seattle Children's

Video Content