Post by Noah Thyberg
Senior TSS; Heart Transplant Recipient & Organ Donation Advocate
One CAR-T cell. Seven cancer cells. Seven hours. This video captures ONE single CAR-T serially killing 7 tumor cells, triggering apoptosis after brief contacts and immediately moving on to the next target—no labels, no endpoints, no phototoxicity. Then comes the part that matters most: only ONE cancer cell survives. That heterogeneity—why some targets succumb while others resist sustained CAR-T pressure—is a central challenge in immuno-oncology and a key limiter of long-term therapeutic success. Recorded using Nanolive’s label-free live-cell imaging platform, this dataset reveals continuous T-cell behavior at high spatial and temporal resolution—showing real dynamics, not assay artifacts. 🎥 Full breakdown with Dr. Roddy O’Connor (UPenn): https://bit.ly/4iYBj4l 🔬 Learn more about Nanolive’s IO imaging workflows: https://bit.ly/4povsaK #ImmunoOncology #CAR_T #TCellBiology #CancerResearch #LiveCellImaging
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