Post by Medical Toxicology

Name: “Benadryl? Worst case they sleep it off.” Wrong! A big diphenhydramine overdose doesn’t sedate — i
Uploaded: 2026-06-24T11:10:14.957Z
Channel: Medical Toxicology
Description: “Benadryl? Worst case they sleep it off.” Wrong! A big diphenhydramine overdose doesn’t sedate — it lights people up. Agitated, flushed, racing heart, blown pupils, grabbing at things that aren’t th

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“Benadryl? Worst case they sleep it off.” Wrong! A big diphenhydramine overdose doesn’t sedate — it lights people up. Agitated, flushed, racing heart, blown pupils, grabbing at things that aren’t there. Red as a beet, dry as a bone, hot as a hare, mad as a hatter. The cartoon’s funny. The patient isn’t. Get the ECG. Expect anticholinergic effects, provide physostigmine or rivastigmine. Treat the patient, not the label. #MedicalToxicology #PoisonCenter #Toxicology #EmergencyMedicine

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