Post by Manus

Biomanufacturing doesn't scale on yield alone. It also depends on how efficiently you recover the product. For certain intracellular products, cell disruption can account for more than a third of total production costs. That makes product recovery a critical factor in the economics of scale. At the most recent BioMADE Member Meeting, Joe Shaw, Senior Vice President of Research and Development at Manus, shared positive results from our Engineered Yeast Lysis Project, conducted in collaboration with Prof. Hal Alper and the McKetta Department of Chemical Engineering, The University of Texas at Austin. The goal of the research was simple: discover ways to recover more product while using less energy, improving the efficiency and speed of commercial-scale production. When evaluated in Manus' pilot plant at our Augusta BioFacility, the results of our research showed: • 56% increase in oil yield • 55% less energy required per gram of recovered oil • 95% total lipid recovery By addressing a key downstream processing bottleneck, this work demonstrates how innovations in cell factory engineering can help make industrial biomanufacturing more efficient, scalable, and economical. Accelerating the transition to BioAlternatives by delivering the benefits of biomanufacturing, today. Learn how this research may help biomanufacturers reduce costs and capture premium value from yeast processes: https://lnkd.in/ek7haVin #MadebyManus #BioAlternatives #biomanufacturing #bioeconomy