Post by The Lister Institute of Preventive Medicine

🔍 What happens when a scientist disproves her own hypothesis? For #ListerFellow Dr Lizzy Rosser, what began as a focused study of B cells in the eye solely in children with arthritis evolved into a broader, more ambitious exploration of B cells in the pathology of childhood autoimmune disease—one that’s as much about people as it is about pathways. Her research is now trying to answer some fundamental questions: 🔬 Why do some children with the rare condition juvenile idiopathic arthritis develop uveitis (an inflammatory eye condition that can cause blindness ) while others do not? 🔬 Are the same immune pathways responsible for autoimmune inflammation in joints and eyes? 🔬 What role do B cells play in driving this inflammation—and can they be targeted to prevent damage? Experimental findings suggest that B cells may influence inflammation in more diverse and tissue-specific ways than previously thought. 👉 Read the full story: https://lnkd.in/efE8GcS2