Post by Leica Microsystems

When multiple users depend on the same EM workflow, consistency matters. This curated eCollection gathers protocols for high-pressure freezing grounded in peer-reviewed publications, plus downstream steps like freeze substitution, electron tomography, and 3D EM analysis. Use it as a common reference to compare approaches, support troubleshoots, and document decisions for publications in shared workflows. Explore the eCollection ➡️ https://fcld.ly/wxr5d2u Caption: 3D rendering of a mouse beta cell with a primary cilium with microtubules (blue, purple), mitochondria (light blue), insulin SGs (orange), endoplasmic reticulum (gray), ribosomes (green), and plasma membrane (transparent). Image courtesy Andreas Müller, doi: https://fcld.ly/v6vd62l