Post by Kiran Raosaheb Patil

Do microbes compete, fight, or cooperate? No matter which, they need to tune their protein machinery to the presence of other species. Yet, we know very little of this molecular orchestration in communities and thus most microbial interactions remain phenomenological observations. Fantastic work led by Stephan Kamrad in our lab published in Nature Portfolio is an important step in changing this: https://lnkd.in/ezBuRSuW Proteomic and metabolomic analyses of 104 pair-wise co-cultures between 15 gut bacteria reveal substantive proteomic remodelling with typically 50% of the proteome changing in response to at least one partner. Many changes in metabolism but also in yet uncharacterised proteins hinting at their ecological roles. For the full resource and much more please see the link below. Teamwork with Simran A. Simone Mozzachiodi Sonja Blasche David Scheidweiler Ph.D. Arianna Basile, Ph.D. Rui Guan Rob Bradley Naomi van den Berg, PhD Michael Muelleder Markus Ralser