Post by Jon Brudvig, PhD

In 1979 Francis Crick called this “impossible.” Now, it’s real. A cubic millimeter of brain tissue. 200,000+ cells. 75,000 functionally imaged neurons. 500 million synapses. All mapped and matched to functional activity. This new MICrONS dataset isn’t just the largest wiring diagram of the mammalian brain ever made. It’s the first time we’ve been able to link structure and function at this scale, combining high-resolution electron microscopy with in vivo calcium imaging, all in the same chunk of visual cortex. They even showed the mouse clips from The Matrix, recorded every spike, and then reconstructed the wiring behind the activity. 📽️ 🐁 🔬 If you care about brain function, AI, or systems biology, this is worth exploring. 🔗 Data & tools (open access): https://lnkd.in/gKQ3W8aR 📄 Paper: https://lnkd.in/guHmvjaP 🧠 News summary: https://lnkd.in/gXFnvxTH If we can map 4 km of wiring in a 1 mm³ cube, how far are we from building models that actually think like brains? #Connectomics #Neuroscience