Post by Jason Y. Wong, PharmD, APP

New edition of In Translation. We celebrate the prescription and almost never the one we take away, yet in my PACE clinic the average patient is on 13 or more medications. The OPTIMISE trial showed patients over 80 could drop a blood pressure medicine and keep the same control, while adverse drug events still send roughly 100,000 older Americans to the hospital each year from four ordinary drug classes. This week I make the case that deprescribing, the disciplined art of doing less, is some of the most precise and equitable work a pharmacist does. It also asks why the fragmented Medi-Cal patients with the most prescribers and the fewest advocates need it most, with a CYP2C19 and proton pump inhibitor spotlight on the genome's quieter argument, for less. #Pharmacy #Pharmacists #Deprescribing #Healthcare #InTranslation #Polypharmacy #MedicationSafety #Pharmacogenomics #HealthEquity #HealthEquity