Post by InnoSyn B.V.

🔬 New Publication | Chiral Crystallization Technologies What if you could convert a racemic mixture into a single pure enantiomer, in virtually quantitative yield, with no chiral auxiliaries? In a peer-reviewed paper in Chemistry Today - Chimica Oggi, InnoSyn B.V. Bernard Kaptein and Ben de Lange present two technologies that do exactly that: ◻️ Viedma Ripening - stir a racemic slurry with glass beads, solution-phase racemization drives full conversion. From weeks to under 1 hour at pilot scale. ◻️ TCID - programmed temperature cycles (5–10 °C) in standard equipment. >98% ee after 32 hours, no special hardware needed. Both break the 50% yield ceiling of classical resolution, require no chiral resolving agents, and recycle the mother liquor for complete conversion, applied to building blocks for Clopidogrel, Prasugrel, Saxagliptin, and many more. 👉 Read the full publication: https://lnkd.in/ehfFC6RG #InnoSyn #ChiralChemistry #Crystallization #Deracemization #ProcessChemistry #Pharma #GreenChemistry #LifeSciences