Post by Infinity Bio, Inc.

Nearly every virus a person encounters leaves a lasting signature in their antibodies. Discover how to profile a blood or serum sample for antibodies against to every known human virus. Infinity Bio's pan-viral antibody reactome assay, VirSIGHT, encodes more than 285,000 peptides drawn from over two million viral protein sequences. One sample can be screened against the full range of human viruses in a single experiment. The validation is what makes it usable for discovery cohorts: • 100% sensitivity across the SARS-CoV-2, HIV-1, and HSV-1 reference cohorts • No false positives in seronegative samples • A mean Pearson correlation of 0.989 across operators, plates, and replicates For epidemiologists and infectious-disease researchers, one assay can map a population's viral exposure history and connect it to health outcomes at biobank scale. The antibody reactome is the responsive layer of immune memory, an amplified and cumulative record of a lifetime of immune encounters. VirSIGHT deciphers its viral chapter. Read the white paper. Link in the first comment.

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