Post by Hannah Pauw
Resident not in training Gastroenterology & Hepatology || PhD candidate Dutch Pancreatitis Study Group || Clinical Epidemiologist
π¨ New publication in BMJ Open Gastroenterology Our multicenter Dutch cohort study investigated whether the gut and oral microbiome at hospital admission can predict complications and severity in patients with acute pancreatitis. π Key findings: β We identified three microbial taxa (Finegoldia, Anaeroglobus, Lachnospiraceae_FE2018_group) robustly associated with severe disease and complications β Many previously reported associations could not be replicated, underlining the importance of standardized methods and reproducibility β Results highlight the need for longitudinal microbiome studies to better understand temporal relationships with disease progression Why it matters: Acute pancreatitis is common and can be life-threatening in severe cases. Reliable microbial markers could help identify high-risk patients early and open doors for microbiome-based diagnostics or therapies. π Read the full open access article here: https://lnkd.in/eBHU-MhH #Microbiome #AcutePancreatitis #Gastroenterology #BMJOpenGastroenterology Hester Timmerhuis Marc Besselink Yama Issa Marco Bruno Pieter Jan de Jonge Harry van Goor Rutger Quispel Wim Van De Vrie Adriaan Tan Muhammed Hadithi Niels Venneman Jeroen Jansen Ben Witteman Thijs Schwartz Roy van Wanrooij Rogier Voermans Alexander Poen Peter van Duijvendijk Marie-Paule Anten Tessa Romkens Elske Sieswerda Merel Tielemans Prof. Jeanin E van Hooft, MD, PhD, MBA Marja Boermeester Robert Verdonk, Hjalmar van Santvoort Fons van den Berg Pancreatitis Werkgroep Nederland / Dutch Pancreatitis Study Group MDL Fonds Gastroenterology at BMJ