Post by Founders Pledge

𝗜𝗻 𝟮𝟬𝟮𝟭, 𝘁𝗵𝗲 𝗪𝗼𝗿𝗹𝗱 𝗛𝗲𝗮𝗹𝘁𝗵 𝗢𝗿𝗴𝗮𝗻𝗶𝘇𝗮𝘁𝗶𝗼𝗻 𝗮𝗽𝗽𝗿𝗼𝘃𝗲𝗱 𝘁𝗵𝗲 𝗳𝗶𝗿𝘀𝘁 𝗺𝗮𝗹𝗮𝗿𝗶𝗮 𝘃𝗮𝗰𝗰𝗶𝗻𝗲. 𝗔𝗳𝗿𝗶𝗰𝗮𝗻 𝗰𝗼𝘂𝗻𝘁𝗿𝗶𝗲𝘀 𝘁𝗼𝗼𝗸 𝗮𝗻 𝗮𝘃𝗲𝗿𝗮𝗴𝗲 𝗼𝗳 𝘀𝗲𝘃𝗲𝗻 𝗺𝗼𝗻𝘁𝗵𝘀 𝗹𝗼𝗻𝗴𝗲𝗿 𝘁𝗼 𝗮𝘂𝘁𝗵𝗼𝗿𝗶𝘇𝗲 𝗶𝘁𝘀 𝘂𝘀𝗲. Many of us are used to a world where if science solves a health problem, we have access to the treatment soon after. Throughout Africa, every drug for every disease faces high regulatory friction, leaving a backlog of thousands of applications stuck in the approval process. In October 2025, the African Medicines Agency launched and, for the first time, Africa has a continental agency with a mandate to harmonize drug regulation across all 55 nations. This opens a rare policy window to build key institutions from the ground up with the opportunity to shape how medicines reach patients in the future. This year, our Catalytic Impact Fund made an initial $70,000 scoping grant to 1Day Sooner to provide technical assistance to the AMA in two areas, with additional funding to follow if the project proceeds. The first is developing AI-assisted regulatory review, which could cut the 278-day first stage of document review down to weeks. The second is enhancing continent-wide guidance on human challenge trials, a fast and inexpensive methodology that generates the local clinical evidence African regulators often require. Read more about our Catalytic Impact Fund's 2026 grants: https://lnkd.in/egchX_ez