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👏This review is the most‑downloaded article among our 2026 publications! 🔅 Title: ESR1 mutations in ER‑positive breast cancer: from endocrine resistance to ctDNA‑guided therapeutic interception 🔅 Full Text: https://lnkd.in/eHW96A4Y This review addresses ESR1‑driven endocrine resistance in ER‑positive breast cancer. It highlights ctDNA‑guided treatment intervention, SERD therapy, PI3K/AKT co‑mutations, as well as ongoing clinical hurdles for precision breast‑cancer care. #ESR1 #EstrogenReceptor #BreastCancer #EndocrineResistance #ctDNA #PrecisionOncology Exploration of Targeted Anti-tumor Therapy Editor-in-Chief: Dr. Nicola Normanno

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