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This #MicrobiomeDay we highlight the critical role of human microbiota in shaping drug response and addressing one of the key challenges in drug development: the limited predictivity of preclinical models. A major missing component in traditional systems is the gut microbiome, which strongly influences drug absorption, metabolism, efficacy, and toxicity. At Evotec, we are tackling challenge gap through human microbiota-driven mouse models that bring preclinical studies closer to human physiology. šŸ”— š——š—¼š˜„š—»š—¹š—¼š—®š—± š˜š—µš—² š˜€š—°š—¶š—²š—»š˜š—¶š—³š—¶š—° š—½š—¼š˜€š˜š—²š—æ š˜š—¼ š—²š˜…š—½š—¹š—¼š—æš—² š˜š—µš—² š—ŗš—²š˜š—µš—¼š—±š—¼š—¹š—¼š—“š˜†, š—³š—¶š—»š—±š—¶š—»š—“š˜€, š—®š—»š—± š˜š—æš—®š—»š˜€š—¹š—®š˜š—¶š—¼š—»š—®š—¹ š—¶š—ŗš—½š—¹š—¶š—°š—®š˜š—¶š—¼š—»š˜€ š—¼š—³ š˜š—µš—¶š˜€ š—æš—²š˜€š—²š—®š—æš—°š—µ: https://okt.to/iqw32R

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