Post by Evan Czulada, MD

Can a simple pacing rate adjustment improve outcomes in patients with HFpEF and persistent AF? That’s the central question behind #OPTRATEAF, our ongoing randomized crossover trial investigating whether conduction system pacing at 80 bpm versus 60 bpm following AV node ablation can improve functional status and quality of life in this challenging-to-treat patient population. We’re measuring 6-minute walk test, KCCQ-12 score, and more to better understand the impact of pacing rate on patient-centered outcomes. Curious about our study design? Our rationale and design paper has been published in the The American Journal of Cardiology! This trial has the potential to reshape how we manage HFpEF in the setting of persistent AF—and we're excited to share that enrollment is already underway! Proud to be working alongside PI Athanasios Thomaides and co-authors Jamal David Smith, MD, MSc., CCRP, PMP, Paul Kolm, Brototo Deb, MD, MIDS, Sarahfaye Dolman, Nebu Alexander, Ryan Braun, Rajiv Kabadi, MD, William Weintraub, and David Strouse on such an important study. #HFpEF #AF #AFib #CPP #CSP #AVNablation #RCT #EPeeps #HeartFailure #Cardiology #Electrophysiology #6MWT #KCCQ https://lnkd.in/eYiR8RCP