Post by Darren Hargrave

Professor at UCL Great Ormond Street Institute of Child Health

Delighted our research, consistent with the hypothesis that Diffuse Midline Glioma (DMG/ DIPG) exploit otherwise healthy brain circuits to promote tumour growth, has just been punished in Nature. This builds on the pioneering work of Michelle Monje and as always was only possible due to multiple collaborations with our wonderful co-authors including Michael Fox (thank you). https://rdcu.be/fnBAf I am also pleased that James Tapper from the Observer has highlighted the leading role in this research from two very talented UCL medical students Jai Sidpra and Valentina Lind who I have had the privilege of supervising. https://lnkd.in/eWZeT6EN https://lnkd.in/esVf-p56 As a clinician who treats children with DMG/DIPG I am very aware how devastating this brain cancer is and we are tirelessly searching for novel ways to improve outcomes and this research opens another avenue for future therapeutic strategies. Our research is now turning to how we exploit these findings to try and develop better treatments. The fight goes on!

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