Post by CTIN (Clinical Trials Information Network)

Where the Sjögren's patients actually are. We estimated the eligible patient pool for primary Sjögren's syndrome across six European markets, then checked it against current trial demand. The pools are not where population alone would predict: → Germany: ~41,348 estimated patients → Spain: ~23,564 → Poland: ~18,469 → Italy: ~18,206 → France: ~7,713 𝗚𝗲𝗿𝗺𝗮𝗻𝘆 𝗵𝗮𝘀 𝟱.𝟰× 𝘁𝗵𝗲 𝗽𝗮𝘁𝗶𝗲𝗻𝘁 𝗽𝗼𝗼𝗹 𝗼𝗳 𝗙𝗿𝗮𝗻𝗰𝗲. The surprise is why. It is not population, France has 68M people. It is prevalence: France's estimate runs at 11.34 cases per million, against 48.99 used for Germany, Spain, the UK and Poland. Same disease, very different epidemiology on record. For Spain, the picture is unusually favourable: → ~23,564 eligible patients → Only ~1.9% of that pool needed to meet current trial demand → 0.7 competing trials per 1,000 patients, low competition Big pool, light competition. On paper, an excellent recruitment environment. The lesson for multi-country allocation: 𝗽𝗮𝘁𝗶𝗲𝗻𝘁-𝗽𝗼𝗼𝗹 𝘀𝗶𝘇𝗲, 𝗻𝗼𝘁 𝗵𝗲𝗮𝗱𝗰𝗼𝘂𝗻𝘁, should drive where sites go. And when one country's prevalence estimate sits 4× below its neighbours, that is a flag worth opening before you plan enrollment. Where would you place your sites first? 👇 🌍 We are CTIN → Clinical Trials Information Network 𝐖𝐞 𝐛𝐫𝐢𝐝𝐠𝐞 𝐄𝐮𝐫𝐨𝐩𝐞'𝐬 𝐜𝐥𝐢𝐧𝐢𝐜𝐚𝐥 𝐫𝐞𝐬𝐞𝐚𝐫𝐜𝐡 𝐞𝐜𝐨𝐬𝐲𝐬𝐭𝐞𝗺 🔍 Follow for clinical research market insights 🤝 Share to support our mission #ClinicalTrials #ClinicalResearch #PatientRecruitment