Post by Cardiff University / Prifysgol Caerdydd

The first patient has been treated in a clinical trial that is testing a pioneering virus technology – which originated at Cardiff University – that infects cancer cells, producing an anti-tumour drug from inside the tumour cells. 👇 Full story in the comments 👇 The new therapy provides a dual-therapeutic effect, by first recognising and infecting only cancer cells, making more copies of itself, causing the infected cancer cells to burst. Secondly, the virus delivers a gene into cancer cells that encodes for a checkpoint inhibitor – a form of immunotherapy that blocks proteins on immune cells. This turns the cancer cells into factories producing the anti-tumour drug and triggering a powerful and precise immune response to act on the tumour. "It’s wonderful to see an invention made at Cardiff University progress into a clinical trial and for one of these sites to be in Cardiff." Professor Alan Parker #CardiffUniversity #PrifysgolCaerdydd