Post by Bram Verstockt

🚨 Ulcerative colitis #UC is NOT purely a mucosal disease 🚨 In our new Viewpoint in The Lancet Gastroenterology & Hepatology, we challenge one of gastroenterology’s oldest dogmas ! Beautiful work by Elisabeth Eggermont, supported by an international group of experts across various disciplines ! 🔬 Intestinal ultrasound, surgical, and histopathological data now reveal transmural involvement in UC — thickened submucosa, fibrotic shifts, mesenteric changes — even in endoscopic remission. 💡 The message is clear: ➡ UC extends beyond the mucosa. ➡ It’s a progressive, deeper disease. ➡ Our treatment goals must evolve with it. Proud of the brilliant teamwork that made this possible — and grateful to colleagues and friends who helped shape this rethink of what UC really is! Elisabeth Eggermont Krisztina Gecse Noa Krugliak Cleveland Frauke Petersen João Sabino André D'Hoore Torsten Kucharzik Mariangela Allocca Gabriele Bislenghi Kerri Novak Gert De Hertogh Christian Maaser IBD Leuven International Bowel UltraSound (IBUS) Group 👉 Read it here: https://lnkd.in/evkfi7sR. #IBD #UlcerativeColitis #TransmuralHealing #Gastroenterology #ChallengingDogma #TeamScience #IUS