Post by Axxam

Cardiac safety is still one of the biggest risks in drug development. And often, the issue starts early—with models that don’t fully capture human physiology. What if you could test compounds in a miniaturized, beating human heart chamber? Using HeartBeat.bio AG's technology, induced pluripotent stem cells (iPSCs) can self-organize into complex 3D cardiac structures known as Cardioids. A 3D, functional model that can be: ✔️Paced with light ✔️Measured in real time ✔️Scaled to 384-well screening → A more controlled, human-relevant way to investigate cardiac function and detect safety risks earlier. We explore how this system works—and why it matters for drug discovery—in our latest newsletter. 👇 Read the full article