Post by A*STAR Infectious Diseases Labs - A*STAR IDL

🦠 𝗢𝘂𝗿 𝗮𝗻𝘁𝗶𝗯𝗶𝗼𝘁𝗶𝗰𝘀 𝗮𝗿𝗲 𝗳𝗮𝗶𝗹𝗶𝗻𝗴. 𝗡𝗼𝘄 𝗯𝗮𝗰𝘁𝗲𝗿𝗶𝗮 𝗮𝗿𝗲 𝗲𝘃𝗼𝗹𝘃𝗶𝗻𝗴 𝘁𝗼 𝗼𝘂𝘁𝘀𝗺𝗮𝗿𝘁 𝗼𝗻𝗲 𝗼𝗳 𝗼𝘂𝗿 𝗻𝗲𝘅𝘁 𝗹𝗶𝗻𝗲𝘀 𝗼𝗳 𝗱𝗲𝗳𝗲𝗻𝗰𝗲 𝘁𝗼𝗼. 𝗣𝗵𝗮𝗴𝗲 𝘁𝗵𝗲𝗿𝗮𝗽𝘆 has been hailed as a breakthrough weapon against 𝗮𝗻𝘁𝗶𝗺𝗶𝗰𝗿𝗼𝗯𝗶𝗮𝗹 𝗿𝗲𝘀𝗶𝘀𝘁𝗮𝗻𝗰𝗲 (𝗔𝗠𝗥). But this new study reveals that 𝘔𝘺𝘤𝘰𝘣𝘢𝘤𝘵𝘦𝘳𝘪𝘶𝘮 𝘢𝘣𝘴𝘤𝘦𝘴𝘴𝘶𝘴 can rapidly switch into a more 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁-𝗿𝗲𝘀𝗶𝘀𝘁𝗮𝗻𝘁 𝘀𝘁𝗮𝘁𝗲, allowing it to 𝗲𝘃𝗮𝗱𝗲 𝗽𝗵𝗮𝗴𝗲 𝗮𝘁𝘁𝗮𝗰𝗸 altogether. The encouraging finding? 💡 The team also showed that a 𝗰𝗼𝗺𝗯𝗶𝗻𝗮𝘁𝗶𝗼𝗻 𝗽𝗵𝗮𝗴𝗲 𝘀𝘁𝗿𝗮𝘁𝗲𝗴𝘆 can overcome this resistance — an important step forward in the fight against 𝗱𝗿𝘂𝗴-𝗿𝗲𝘀𝗶𝘀𝘁𝗮𝗻𝘁 𝗶𝗻𝗳𝗲𝗰𝘁𝗶𝗼𝗻𝘀. 🔬 Proud to share this work from our team at A*STAR Infectious Diseases Labs - A*STAR IDL, alongside collaborators from Lee Kong Chian School of Medicine, National University of Singapore, and international partners. Published in Proceedings of the National Academy of Sciences and featured in an expert commentary, this study advances the scientific foundation for 𝗻𝗲𝘅𝘁-𝗴𝗲𝗻𝗲𝗿𝗮𝘁𝗶𝗼𝗻 𝗔𝗠𝗥 𝘁𝗵𝗲𝗿𝗮𝗽𝗲𝘂𝘁𝗶𝗰𝘀 and strengthens global 𝗽𝗮𝗻𝗱𝗲𝗺𝗶𝗰 𝗽𝗿𝗲𝗽𝗮𝗿𝗲𝗱𝗻𝗲𝘀𝘀 efforts. 🌏 As resistant pathogens continue to evolve, understanding 𝗵𝗼𝘄 𝘁𝗵𝗲𝘆 𝗲𝘀𝗰𝗮𝗽𝗲 𝘁𝗿𝗲𝗮𝘁𝗺𝗲𝗻𝘁 — 𝗮𝗻𝗱 𝗵𝗼𝘄 𝘁𝗼 𝘀𝘁𝗮𝘆 𝗮𝗵𝗲𝗮𝗱 𝗼𝗳 𝘁𝗵𝗲𝗺 — has never been more critical. 🔗 Study and commentary links in the original post below. #AMR #PhageTherapy #AntimicrobialResistance #InfectiousDiseases #PandemicPreparedness #ASTARforSG Pablo Bifani, Jun Hao Liew, Nurul Ayuni Norman, Morgane Illouz, Teck Hui Teo, Riccardo Delli Ponti, PhD, Claire HAMELA, Lalit Mohan, Renee L., Chanvutha Ron, Kay En Low, Wassim Daher, Aryeh Chiam, Joanna Maw, Yan Sun, Ria Sorayah, Stefan Oehlers, Byung Woo Jhun, Jeanette W. P. Teo, Adeline Goulet, Isabelle Guerin-Bonne, René Wintjens, Kevin Pethe, Roland G. Huber, Laurent KREMER