Post by AAPS Open

Transdermal drug delivery system of lidocaine hydrochloride based on dissolving gelatin/sodium carboxymethylcellulose microneedles | AAPS Open by Shabnam Bahmani, Ramin Khajavi, Morteza Ehsani, Mohammad Karim Rahimi, and Mohamadreza Kalaee Highly viewed and highly cited since its publication in 2023, this study develops dissolving microneedles based on gelatin and sodium carboxymethylcellulose for transdermal delivery of lidocaine hydrochloride. The optimized formulation achieved complete drug release in under 10 minutes while maintaining adequate mechanical properties, positioning this system as a potential option for rapid local anesthesia before minor skin procedures. 🔗 Read the full article: https://lnkd.in/gf88FjJ4 #Microneedles #Transdermal #DrugDelivery #Formulation #OpenAccess American Association of Pharmaceutical Scientists (AAPS) | @aapscomms Yongchao Su Mo Maniruzzaman Xiuling Lu Yihong Qiu Dana Moseson-Tarrh Chun-Wan Yen Marina Irène Ostankovitch