Singapore
I’m a Biological Sciences graduate (BSc Hons, NTU ‘24, CGPA: 4.42/5.00, Second Class Upper Honours) with a Second Major in Biomedical Structural Biology, passionate about advancing knowledge on infectious diseases and their impact on human health. With 10 months of wet lab experience (E. coli culturing, PCR, miniprep, membrane protein purification) and a 6-month A*STAR internship, I’ve honed skills in bioinformatics through flaviviral protein modelling (GROMACS, VMD) and bacterial gene expression analysis (Python). My research output includes co-authoring papers in Structure (2024) and Journal of Molecular Biology (2021), focusing on bacterial protein complex structures and transcriptomics, respectively. Under the ARIA program at A*STAR’s Bioinformatics Institute, I modelled flaviviral envelope proteins, contributing structural insights for virology research, and collaborated to optimise simulations on the NSCC supercomputer. Comparing in silico protein behaviour in flat versus curved membranes revealed that a significant epitope was more exposed in the curved set-up — hinting at physiological relevance for immunology research. During my FYP at NTU, I expressed and purified E. coli membrane protein complexes for structural studies while collaborating and learning broadly from lab members. I also broke through a major project deadlock by drawing connections across literature and concepts from an unrelated module. This study of a potential regulator of a protein quality-control protease culminated in a paper published in Structure (2024), where I earned the position of second author for my contributions. This journey was fuelled by my longstanding drive to explore infectious diseases and virology, inspiring the hands-on and computational research I’ve pursued. I’m particularly eager to master multi-omics skills to advance pathogen studies, and am also curious about cancer and ageing biology as areas to explore. I also bring strong teamwork and organisational skills from my role as Quartermaster for NTU’s Canoe Polo team, where I managed equipment and repairs while reducing damages by 50%. My subsequent appointment as the club's Business Manager built upon these skills while unlocking skills in budget management and stakeholder management. Both experiences aimed to ensure smooth running of the club while collaborating within the 8-member exco team, thus refining my problem-solving and communication skills as well. Let’s connect to explore opportunities in virology, infectious diseases and bioinformatics!
Conducted computational research on flaviviral envelope proteins at A*STAR’s Bioinformatics Institute, contributing to virology studies for infectious disease applications. • Modeled protein-membrane interactions using GROMACS and VMD, optimizing EnCurv plug-in parameters for curved lipid bilayer simulations. • Ran simulations on the National Supercomputing Centre (NSCC) supercomputer, ensuring efficient data processing for large-scale molecular dynamics. • Worked closely with my mentor and team to benchmark simulation parameters, supporting structural insights for antiviral research.
Managed finances for NTU’s Canoe Polo team, improving operational efficiency and fostering team collaboration. • Managed and grew club fund by 20% from four initiatives • Directed and approved purchases made by the club • Created and communicated the annual spending budget with the club exco (8 members) to gather feedback and refine the budget • Adjusted members' quarterly club fees according to projected spending to maintain the club fund while working towards longer-term goals • Sourced sponsorships for three competitions to support competition funding • Successfully secured sponsorship deals from 60% of potential sponsors • Developed strong teamwork and communication skills through coordination with team members and external stakeholders.
Managed equipment for NTU’s Canoe Polo team, improving operational efficiency and fostering team collaboration. • Oversaw inventory and upkeep of training equipment such as boats, paddles, and balls • Enforced proper care of training equipment, reducing damages by 50% while improving leadership skills • Established an online reporting system to streamline the fault reporting process, making the damage repair pipeline more efficient • Coordinated logistics between 4 major stakeholders for 3 events, honing communication skills • Developed strong teamwork and communication skills through coordination with both internal and external stakeholders.
Developed Bacteria.guru, a comparative transcriptomics and co-expression database for 20+ bacterial pathogens, published in the Journal of Molecular Biology (2021) as part of NTU’s BS1009 Computational Thinking Internship (Extended Project). This mini-internship experience aimed to compile the publicly available transcriptomic data of 20+ species of bacterial pathogens into a single online database. Allowing open-source query of gene co-expression networks of significant bacterial pathogens under different conditions supports infectious disease research by enabling gene function and regulation analysis. • Created Python code to process transcriptomic data of 3 bacterial species under different conditions • Collaborated with 9 research groups to build a database covering 20+ bacterial species using Python, enhancing data accessibility and visualisation for gene expression studies. • Drafted manuscript in a major collaborative effort, gaining hands-on experience in drafting scientific literature