Yiyuan Li

Bioinformatics | Genomics | Sequencing | Metagenomics | Evolutionary Biology

Notre Dame, Indiana, United States

About

► Innovative, problem-solving biology Ph.D. student with 9 years of training in bioinformatics, genomics, and genetics ► Strong skills with next-generation sequencing data analysis, including RNA-seq and metagenomics ► Hands-on experience in a wide range of analytical techniques, including Perl, Python, R, Shell scripting and statistics

Experience

  • Professor at Ningbo University
    Jun 2022 - Present · 4 yrs 2 mos

  • Postdoctoral Researcher at The University of Texas at Austin
    Sep 2018 - Sep 2021 · 3 yrs 1 mo

  • Graduate Research Assistant at University of Notre Dame
    Aug 2013 - Aug 2018 · 5 yrs 1 mo

    Fish Biodiversity Assessment with Environmental DNA - Investigated fish biodiversity via environmental DNA and NGS to monitor endangered and invasive species resulting in 1 first-author and 4 co-author papers published in scientific journals - Species assignment optimization: applied data mining algorithms (including Decision Tree, Naïve Bayes, and Sequential Minimal Optimization) to fast and accurately identify fish species - Developed bioinformatics pipelines to improve assembly and annotation for mixed mitochondrial genomes - Built bioinformatics pipelines to analyze batch metagenetic samples in parallel (>200 samples) based on Sun Grid Engine Insect Oxidative Phosphorylation Evolution Study with RNA-seq - Studied functional gene evolution in large-scale of insect lineages across 4 insect orders using RNA-seq with 1 first author paper and 1 co-author paper published in scientific journals - Performed assembly, annotation, variant calling, testing gene family evolutionary rate, gene family expansion and contraction analysis - Collaborated with corporate partner, BGI, on the 1000 Insect Transcriptome Evolution project

  • BGI-Shenzhen (3 yrs 4 mos)
    • Bioinformatics Researcher
      Jul 2011 - Jun 2013 · 2 yrs

      - Developed a PCR-independent approach that reduced the false positive rate of metabarcoding - Built bioinformatics pipeline to assemble and annotation mitochondrial genomes

    • Internship
      Mar 2010 - Jun 2011 · 1 yr 4 mos

      - Investigated gut microbiome difference between premature and fullterm infants using metagenomics and qPCR - Developed bioinformatics pipeline for 16S rRNA gene analysis