William Oh

Director, Precision Medicine | Professor | Prostate Cancer Leader

New Haven, Connecticut, United States

About

My professional mission is to leverage my expertise and passion for advancing cancer care and research to improve the lives of patients and their families in local communities and around the world. I recently joined the Yale Cancer Center as Professor and Director, Precision Medicine and Senior Advisor to the YCC Director. I am also Service Line Medical Director at Smilow Cancer Hospital at Greenwich, leading a strategic approach to cancer program building. As a board-certified medical oncologist with >25 years of clinical and translational research experience, I held previous leadership roles at Harvard and Mount Sinai, developing innovative clinical trials and clinicogenomic databases to build novel approaches to treating cancer. As Chief Medical Officer at the publicly-traded health intelligence company, Sema4, I drove adoption of precision medicine integrating genomics and clinical data. As the inaugural CMO for the Prostate Cancer Foundation, I led efforts to reduce mortality by focusing on implementation efforts in screening for Black men in the US as well as delivering combination therapy to patients with metastatic hormone-sensitive disease.

Experience

  • Yale School of Medicine (Full-time · 1 yr 9 mos)
    • Director, Precision Medicine, Yale Cancer Center
      Oct 2024 - Present · 1 yr 9 mos

      I am focused on building a cohesive program in precision cancer medicine, integrating basic and translational science, clinical trials, and Smilow Cancer Hospital’s Precision Medicine Tumor Board. Increasing the routine use of molecular and genetic testing for all patients with cancer will improve patient outcomes.

    • Professor of Internal Medicine (Medical Oncology and Hematology )
      Oct 2024 - Present · 1 yr 9 mos

      Delivering outstanding multidisciplinary care for prostate cancer patients has been a priority for my whole career. I have been consecutively honored as a Top Doctor by Castle Connolly, New York Magazine and most recently, Connecticut Magazine. I will continue my teaching and research as well.

  • The Jean and David W. Wallace Medical Director, Smilow Cancer Hospital at Greenwich Hospital at Smilow Cancer Hospital
    Oct 2024 - Present · 1 yr 9 mos

    In this role, I will continue to grow outstanding integrated oncology care teams and expand the impact of multidisciplinary cancer care for patients in the region.

  • Chair, Clinical Advisory Board at Previvor Edge
    Jan 2025 - Present · 1 yr 6 mos

    Previvor Edge is an innovative startup focused on a technology-enabled clinical program for assessing and addressing cancer risk by early detection and prevention.

  • Chair, Scientific Advisory Board at Nature's Toolbox, Inc. (NTx)
    May 2024 - Present · 2 yrs 2 mos

    NTx Bio has developed benchtop platforms for creating personalized RNA vaccines that will help cancer investigators and patients. I am helping them to collaborate with top academic centers to accelerate this technology to improve patient outcomes.

  • Founding Chair, Scientific Advisory Board at Archetype Therapeutics, Inc.
    Jan 2023 - Present · 3 yrs 6 mos

    As Chair of the SAB, I am helping Archetype use their novel AI-generated modeling platform to screen billions of drugs to predict the best drugs for unmet medical needs like prostate and lung cancer.