Kufstein, Tyrol, Austria
• Successful biotech plant management - continuous fermentation of lacic acid bacteria GMP+ & GMP antibiotic oral paste • Optimizing fermentation processes, growth medium & increasing production volume respectively • Documentation of manufacturing specifications on GDP levels • I strive for a professional career allowing me to merge my passion for molecular biology & enthusiasm to initiate & optimize manufacturing processes in an applied pharma context • Genetics are the origin of every action a living cell executes – Since 2010 my intention was to acquire a toolbox filled with essential molecular biologic knowledge & methods allowing me to conceive fast innovative avenues to solve problems or challenging duties • Thinking ahead & face tasks open-minded avoids production losses & ensures a flawless product! • For my curiosity & eager to improve myself by continuously learning the way to life science was my best decision because it is such an interesting area • Teamwork is mutually enriching when everyone do one´s stint - I assist proactively colleagues by sharing my knowhow about process optimization & molecular biology • Create a motivating environment by coaching & supporting my team members is topical • In pharma business it is mandatory for me to provide professional social interaction with colleagues, experts, customer & authority audits • Smart communication & gentle determination is the key to success
Business Unit NTO BIOTECHNOLOGY - Novartis Technical Operations (NTO) NTO manages the production of our Innovative Medicines and Sandoz Division products
GMP+ ready-made product Oralin: 3 fold increase in production quantity (probiotic Enterococcus faecium bacteria) GMP+ Supervision of producing probiotic dietary feed supplements for cats, dogs & livestock on oil basis GMP manufacturing of anitbiotic paste on water basis for horses
Continous fermentation of probiotic Enterococcus faecium bacteria - ready-made product Oralin Manufacture of probiotic dietary feed supplement on oil basis for cats & dogs Manufacture of probiotic & iron containing dietary feed supplement on oil basis for livestock Manufacture of anitbiotic paste on water basis for horses
Project Manager - Clinical Trial Phase II, ProFem GmbH Administration and organization of daily correspondence and meetings with CRO´s, consulters & study centres. Evaluation of a probable time frame to finish patient recruiting by using a landing page and an AdWords campaign. Restructuration and adaption of phase I study documents for a phase II multicenter study and accordingly to regulatory authority demands.
•Identification and verification of miRNAs as biomarkers in human serum samples by designing a tailor made RT-qPCR assay suitable for analysis with qPCR and digital PCR devices. •Establishing a digital PCR method for an absolute quantification of miRNA abundances, originated from first project as a spinoff project.
siRNA screen in human cancer cell lines with oligonucleotide combinations for therapeutic approaches Applied methods & learned skills: human cell culture, small interference RNA synthesis, RNA silencing via transfection, RNA extraction, gene expression analysis with RT-qPCR [reverse transcriptase quantitative PCR], signalling pathway analysis, proliferation & cytotoxicity assays, FACS [fluorescence-activated cell sorting], plasmid construction for gene overexpression, sequencing. Supervision of diploma students throughout their practical work and tutor contracts for several courses.