Munich, Bavaria, Germany
• Led an interdisciplinary research group that pioneered in situ high-resolution imaging and computational analysis of neuronal cells, and elucidated a novel form of synaptic protein organization • Deep conceptual understanding and practical experience in several fields of biology, physics and mathematics • Extensive computational expertise in designing and executing procedures that include 3D image processing, multidimensional data analysis, machine learning and scientific computing; experience in academic and industry environments
• Designed, performed and supervised research that combined biological experiments and structural biology with developing novel computational and analytical approaches to pursue fundamental neurobiological questions • Processing of extremely noisy biological 3D images and multidimensional datasets using image reconstruction, segmentation, template-free feature extraction, clustering, classification, structure determination and validation, multivariate data analysis and visualization, statistical inference, deep learning and spatial point processes • Image processing software: SerialEM, IMOD, EM, Eman, Relion, Spider, ImageJ, Paraview • Obtained prestigious external funding, published more than 30 papers including the top-level journals, gave more than 30 talks, reviewed biological, computational and deep learning manuscripts and grant applications for top level journals and funding agencies • Supervised and trained postdoctoral researchers, PhD students and master students that continued their careers in academia and industry • Expanded understanding of biological disciplines by collaborating with scientists in Germany, Europe and globally
• Performed 3D stochastic and deterministic simulations to develop a realistic model of the activation of a key protein in synaptic plasticity • Performed biochemical essays, and acquired expert understanding of biochemical signal transduction pathways at synapses and fundamentals of neuroscience
Software development and testing
Software testing
Programmed, trained and tested artificial neural networks