Greater Chennai Area
• A result oriented, creative, & highly motivated synthetic organic and medicinal chemist. • Highly productive & problem solving capabilities with 27years of industrial experience. • Extensive hands-on bench experience in synthetic chemistry, oversee the efforts of an associate chemists to ensure the timeline adherence, project alignment to meet group and goals with a highly flexible and results oriented. • Design, plan and execute multi-step organic synthesis (Chiral/Achiral) and purification of target molecules for biological screening. * Devise new or improved routes to target compounds, independently and rapidly. Originate novel ideas or approaches to the scientist’s assigned projects * Modify reaction conditions in accord with visual observatioins and analytical data interpretations to allow rapid, successful production of target compounds * Involved in developing robust method of scale up of active new chemical entitites and made 100g -1Kg of materials • Drug development towards Medicinal chemistry and SAR studies. Modulate physicochemical properties to improve ADME outcomes • Strong interpersonal skills and ability to effectively communicate across disciplines. * Present quality written documentation, methods, validation reports, data reports and summaries * Interact effectively with a analytical/biology/DMPK and project team
Synthesis of Orthogonally / Quasi-orthogonally protected aminoacid building blocks for peptide (API, cosmetics, med chem), di, tri and tetra in LPPS / SPPS and their impurities
API & it's impurities
API & it's impurities and CRAMS
Handling FTE, FFS and custom synthesis. Preparation and review of project updates, campaign reports etc. Resource planning, route scouting, timely delivery, trouble shooting effective communication to customers
Process Optimisation, Development of API heterocyclic, building blocks of peptide and impurities Credential of Indian patent IN578164 B1 An Improved Process for the preparation of Saroglitazar AL Prasad, VM Anand, RG Kamalakar, P Venkatesan, VR Dhavalkukar, AK Ramizhusen