United States
Analytical Chemist, Analytical Research and Drug Development
Discovery Analytical Research - Led a dynamic team of analytic chemists to accelerate drug discovery
-Developed analytical strategy and workflows to enable HTE within discovery chemistry -LC-HRMS characterization of RNA and macrocyclic peptide modalities
-Analytical program lead and team member for several preclinical and clinical programs -Developed chromatography and wet chemistry methods to enable the GMP chemistry synthetic routes, stability assays, and release assay -Developed impurity control strategy including performing the fate and purge of key impurities and degragants to meet ICH safety guidelines -Developed Mutagenic impurity control strategy for several early and late stage programs -Continual education and new employee training team member
Working in a GMP environment, performed analytical testing on APIs, intermediates, raw materials, and in-process reaction samples to enable the pilot plant production of clinical candidate materials
Collaborated with toxicologist, synthetic chemists, medical doctors, and hazard communication specialist to determine sufficient toxicological, physical/chemical, and medical data needed for a MSDS