Mainz, Rhineland-Palatinate, Germany
Tim Sparwasser is Professor at Johannes Gutenberg-University Mainz, and Director of the Institute for Medical Microbiology and Hygiene. He obtained his MD from the Johannes-Gutenberg University in Mainz and studied human Medicine in Mainz, Basel, New York and Munich (Ludwig-Maximilians University). With a fellowship from the Howard Hughes Medical Institute he did a Post-Doc in the laboratory of Dan Littman at the Skirball Institute (New York University). After completing his specialization at the Institute of Medical Microbiology (Director Hermann Wagner), Technical University Munich, he was appointed W3 professor at Hannover Medical School in 2008. His main research interest is investigating novel vaccination strategies with a special focus on dendritic cells and regulatory T cells. His work has led to the discovery of CpG Oligonucleotides as potent adjuvants and activators of dendritic cells. The development of the DEREG mouse model allowed to prove the role of regulatory T cells during infection and (anti-cancer) immunity and shed light on their development and relevance for maintenance of peripheral tolerance. Only recently his team discovered a new mechanism of immune modulation of pro-inflammatory Th17 cells using small natural compounds that interfere with fatty acid metabolism and allow the generation of anti-inflammatory Foxp3 regulatory T cells. https://www.unimedizin-mainz.de/medizinische-mikrobiologie-und-hygiene/forschung/infektionsimmunologie-sparwasser-labor.html
https://www.unimedizin-mainz.de/medizinische-mikrobiologie-und-hygiene/forschung/mitarbeiter-cvs/univ-prof-dr-med-tim-sparwasser.html
https://www.unimedizin-mainz.de/medizinische-mikrobiologie-und-hygiene/infektionsmedizin-diagnostik-und-patientenversorgung/transportmedien-probengewinnung-und-transport/kontakt-anfahrt/institutsleitung.html