Paris, Île-de-France, France
My current research focuses on autophagy, a major recycling pathway that prevents accumulation of cytoplasmic trash in cells. I am particularly interested in molecular mechanisms and membrane trafficking events involved in the process. My laboratory aims to reconstitute autophagy from purified components and model membranes in the test tube. Specialties: Biophysical Chemistry, Structural Biology
Membrane Biochemistry and Transport, Department of Cell Biology and Infection
Equivalent to Assistant Professor. Biomedical research, training of PhD-students, Post-Docs and visiting students (including Bachelor and Master). Teaching at Ludwig-Maximilians-University (Munich, Germany).
In vitro reconstitution of the Endosomal Sorting Complex Required for Transport (ESCRT) machinery on giant unilamellar vesicles.
Rational design of the bacterial virulence factor Internalin to enable its interaction with mouse E-cadherin. Listeria monocytogenes expressing the murinized Internalin are infectious for mice and were used to study listeriosis in a murine model system.
Diplom in Biochemistry (equals Master of Science in Biochemistry). Majors: Biophysical Chemistry and Pharmacology