Gothenburg, Västra Götaland County, Sweden
Creative Immunologist currently working in compound screening and Mechanism of Action studies. In my previous work in academia I investigated immune cell signaling in Mast Cells and Innate Lymphoid Cells. I like to tell a compelling story when I present my data and believe that working together is key to success in R&D!
Discovery Sciences - Mechanistic and Structural Biology (MSB) Department: In this role I am continuing to support high profile projects with compound screening data generated in complex primary cell systems. Additionally I am taking on scientific leadership in drug discovery projects and have taken on operational responsibility by overseeing the business needs regarding our data analysis software (internal system owner).
Discovery Sciences (DS), Mechanistic Biology & Profiling (MBP) Department: In this role I have been supporting drug discovery projects in various therapy areas, such as the respiratory or cardiovascular space, with continuous compound screening and compound mode of action studies. In addition I have supervised an industrial placement student in a project I developed. During the pandemic I supported the Covid-19 screening facility with flexible data analysis that was incorporated into the Swedish national testing data.
Innovative Medicines (iMED), Respiratory, Inflammation and Autoimmunity (RIA) Department: My project concerned cell signaling in type 2 innate lymphoid cells isolated from human peripheral blood. As these are rare cells in healthy donors I am employing cell sorting to obtain a pure population to put in culture for further experiments. The rarity also required me to optimize all downstream experiments for input with low cell numbers. During my time as a Postdoc I also supported a small scale clinical study which resulted in a high impact publication.
INITIATE (innate-immunometablism as antiviral target) is an innovative training network funded by the European Commission with the goal to train a new generation of young researchers in the emerging field of antiviral immunometabolism. In this program I am supervising an industrial PhD student working at AstraZeneca and co-supervising several academic PhD students working all over Europe.
Postdoctoral Research Assistant in the lab of Prof. Dario Alessi FRS at the Medical Research Council Protein Phosphorylation and Ubiquitylation Unit (MRC PPU). In my projects I employed mass spectrometry approaches to identify novel interaction partners of kinases in mouse tissues and cell lines. Results were confirmed by western blotting and protein overexpression in cell lines. In addition I supported the public outreach of the institute by attending school visits and science fairs.
Ph.D. student in the lab of Prof. Michael Huber at the Institute for Biochemistry and Molecular Immunology. I worked on cell signaling in primary mast cells isolated from mouse femurs or peritoneum. My work was centered around modulation of PI3K signaling and how this pathway can influence downstream signaling of other receptors that are not primarily relying on PI3K signaling for their signal transduction.