Greater Boston
I am a driven Scientist in Assay Development at Quanterix developing bead based immunoassays. I obtained my Ph.D in Interdisciplinary Neuroscience (College of Pharmacy) at the University of Rhode Island. During my Ph.D., I evaluated the neuroprotective and anti-inflammatory therapeutic efficacies of small molecules and natural product derivatives using target centric and proteomic approaches. I also have industry experience quantifying biologics with ligand binding assays.
Development of bead based immunoassays for ultrasensitive biomarker detection. Assay design including spike recovery, dilution linearity, and sample testing. Characterization of antibody binding with Octet BLI.
Researched the neurobiological and anti-inflammatory effects of natural phytochemicals using target-centric and screening based approaches. Techniques utilized include ELISAs, biophysical screening (small molecule-protein, and protein-protein) using SPR and MST, bottom-up proteomics, cell-based assays, enzymatic assays, and molecular docking.
Teaching assistant to students in the Cannabis Studies Certificate Program assisting the following courses: Foundations of Cannabis Studies, Cannabis Product Development, Cannabis Chemistry and Pharmacognosy, and Cannabis Therapeutics.
Teaching Assistant to undergraduate students in Introductory Chemistry Laboratory (CHM 105). Teach laboratory material. Maintain laboratory safety. Complete grading of laboratory assignments.
Quantitative ligand binding assay development and sample screening for large molecule new biologic entities using ELISA, Gyros, MSD and SP-X. Custom fit for purpose assay development to compare bioanalysis technologies for quantification of a drug candidate in the discovery research pipeline.
Conducted research on a weekly basis under the direction of Dr. Steven Symington. Developed routine lab skills such as preparation of a serial dilution, statistical analyses, calculations, animal husbandry and preparation of buffers. Performed Drosophila survival bioassays with concentrations of antibiotics and pesticides.
Facilitated study groups and individual tutoring sessions for students in General Biology, Genetics, Statistics and Psychology. Communicated with professors to monitor student progress and promote enhancement of student learning.
Conducted an independent research project studying the toxicity of a diamide antibiotic in relation to known antibiotics and pyrethroid pesticides in Drosophila. Performed statistical analyses and created graphical representations of research findings using GraphPad Prism. Presented research findings through a poster presentation at 11th Annual RI SURF Conference to professors and research fellows.
Conducted research studying the molecular mechanisms underlying motor neuron wiring during embryonic development in mice in Dr. Jaworski’s Lab at Brown University. Performed laboratory techniques such as embryo harvesting, genotyping, embedding and cryosectioning, immunohistochemistry and imaging. Presented research findings through a poster presentation at 12th Annual RI SURF Conference to professors and research fellows.