Tess Linden, Ph.D.

Software Engineer

San Francisco Bay Area

About

Experience

  • BigHat Biosciences (Full-time · 2 yrs 6 mos)
    • Software Engineer II
      Mar 2026 - Present · 5 mos

    • Data Scientist
      Feb 2024 - Jun 2026 · 2 yrs 5 mos

  • Climax Foods (Berkeley, California, United States)
    • Computational Biologist
      Nov 2022 - Jun 2023 · 8 mos

    • Scientist - Microbiology
      Feb 2022 - Oct 2022 · 9 mos

  • University of California, Berkeley (5 yrs 5 mos)
    • PhD Researcher
      Aug 2016 - Dec 2021 · 5 yrs 5 mos

      Advisor: Prof. Nicole King Project 1: "The evolutionary origin of collagen" - Programmatically combed a publicly available proteome database, UniProt, for evidence of collagen proteins in non-animal species in order to investigate the widespread claim that collagen is unique to animals - Found that collagens are common in animals' close relatives and present across diverse non-animal eukaryotes, including fungi and algae - Used bioinformatic analyses to identify the biochemical characteristics of collagen genes outside animals Project 2: "Light-regulated contractility in a newly discovered multicellular choanoflagellate" - As part of a highly collaborative 3-person team, discovered a new species of choanoflagellate (a type of eukaryotic microorganism) and published a high-impact paper on its cell biology only one year later - Used bioinformatics & drug treatments to successfully characterize its vitamin A biosynthesis pathway and thereby determine media components required for its photoresponsive contractile behavior in culture - Designed creative drug & bacterial experiments to identify the receptor proteins & second messengers of the phototransduction pathway

    • Graduate Student Instructor
      2017 - 2018 · 1 yr

      - Worked for two semesters as a GSI (teaching assistant) for the undergraduate course MCB 104: Genetics, Genomics, and Cell Biology - Designed lesson plans that were used by me and other GSIs (including in years following) for weekly discussion sections - Wrote unit tests and contributed questions to midterms and final exams - Earned "Outstanding GSI Award" from UC Berkeley

  • Teaching Assistant at Marine Biological Laboratory
    Jun 2019 - Jul 2019 · 2 mos

    - As TA for the Physiology Course, mentored 4 PhD students from other universities in conducting molecular & cell biology experiments with choanoflagellates - Helped the students design experimental plans and learn microscopy & cell biology techniques

  • Postgraduate Researcher at La Gamba Tropical Station
    Aug 2015 - May 2016 · 10 mos

    Advisor: Prof. Santiago Ramirez (UC Davis) - Extracted tropical orchid scent mixtures for GCMS analysis to determine their chemical composition - Designed artificial mixtures of commercially available volatile compounds to replicate orchid scents - Designed & executed experiments to test effects of scent mixtures on pollinator attraction