Antwerp Metropolitan Area
CMC leader with 10+ years of experience in biopharma, specializing in drug substance development and CMC leadership across multiple modalities, including small molecules, Cell & Gene Therapy, peptides, and lentiviral vectors. Proven track record in delivering IND/CTA submissions and leading cross-functional global teams and CDMO networks in fast-paced environments. Strong expertise in CMC strategy, external manufacturing, tech transfer, and regulatory alignment, with a focus on clinical readiness and operational excellence. Recognized for building high-performing teams and driving execution of complex programs from early development through clinical readiness.
Leading cross-functional CMC teams in the development and execution of CMC strategies for innovative Cell & Gene Therapy programs. Responsible for end-to-end CMC delivery.
Led drug substance development across small molecules and lentiviral vectors, supporting multiple clinical-stage programs. Focused on delivering high-quality CMC packages and ensuring reliable clinical supply through effective CDMO network management. Key contributions: Managed a global CDMO network (10–15 partners) Delivered drug substance for 10+ (pre)clinical programs with 100% on-time milestones Led development activities including solid-state (small molecules) and LVV (plasmids, cell banks, manufacturing readiness) Contributed to IND/CTA submissions and regulatory responses
Managed peptide API development programs from early development through GMP manufacturing. Acted as key interface between internal teams and external partners to ensure timely and high-quality delivery. Key contributions: Designed and executed peptide process development (liquid & solid phase synthesis) Delivered multiple tech transfers and GMP batches Coordinated external analytical activities (method development, validation, impurity profiling) Supported GMP manufacturing, including deviations and validation documentation
Worked on process improvement of polyvinyl butyral (PVB) manufacturing for laminated safety glass (Saflex® interlayer). Key contributions: Improved manufacturing processes to enhance efficiency and product quality
Conducted advanced research in organic chemistry, focusing on synthetic methodologies and catalysis. Key contributions: Developed innovative approaches in synthetic chemistry Collaborated in an international research environment