Greater Madrid Metropolitan Area
I undertook my graduate studies at the National Center for Cardiovascular Disease, supervised by Dr. David Sancho and Dr. Salvador Iborra. Thesis title: Disturbed mitochondrial dynamics in CD8+ T cells impacts antiviral immunity. During my doctoral thesis, I have also developed two other projects focused on the analysis of cross-presentation in dendritic cells. I have worked with numerous in vivo mouse models of disease and have experience working in a biosafety level 2 laboratory (vaccinia and influenza virus infection models, cutaneous leishmaniasis by intradermal injection of Leishmania major, house dust mite mediated allergy). I am an expert in flow cytometry, confocal imaging, cell culture and molecular biology techniques. I have mentored an undergraduate student and a visiting PhD student during short research stays in the lab.
I worked in the laboratory of Dr. David Sancho investigating the role of mitochondrial function in CD8+ T cell antiviral responses.
Master’s thesis: “Batf3-dependent dendritic cells are dispensable for tolerance to house dust mite”. Supervisors: Dr. David Sancho Madrid and Dr. Laura Conejero Hall.
I studied the role of type 1 conventional dendritic cells (cDC1) in the onset of allergic airway inflammation to house dust mite in mouse and optimized and tested nanoparticle based vaccines that target cDC1 in the laboratory of Dr. David Sancho. Bachelor's thesis: “Absence of BATF3-dependent dendritic cells impairs Th1 response to house dust mite and exacerbates asthma”. Supervisors: Dr. David Sancho Madrid and Dr. Laura Conejero Hall.
I evaluated the expression of Wnt11 in mouse intestinal development and self-renewal in the group of Prof. Dr. Konrad Basler. Techniques used included confocal microscopy, as well as fluorescence activated cell sorting and quantitative real-time PCR.
Research internship in Prof. Dr. Luis Menéndez Arias working in the characterization of HIV-1 retrotranscriptases resistant to antiretroviral drugs used in therapy against Acquired Immune Deficiency Syndrome.