Simon Liang

Manager Program Management at Tango Therapeutics

Boston, Massachusetts, United States

About

With over 10 years of experience spanning academia and industry, I focus on drug discovery and early development, including target validation, lead optimization, and preclinical IND-enabling studies to support regulatory filings. My dedication to scientific advancement extends to mentoring aspiring scientists, promoting knowledge-sharing, and inspiring the next generation of researchers.

Experience

  • Tango Therapeutics (Boston, MA · Hybrid)
    • Manager Program Management
      Jan 2026 - Present · 7 mos

    • Manager R&D Operations
      Feb 2022 - Jan 2026 · 4 yrs

  • Novartis Institutes for BioMedical Research (NIBR) (Cambridge, MA · On-site)
    • Senior Scientist I
      Apr 2021 - Feb 2022 · 11 mos

      At Novartis Institutes for BioMedical Research, I played a pivotal role within Oncology Pharmacology/Oncology Drug Discovery to advance the drug discovery pipeline through independent in vivo experiments. My work involved utilizing xenograft tumor mouse models to evaluate drug efficacy and pharmacokinetics, while also leveraging genetically engineered transgenic mouse models to enhance pharmacodynamics research. Collaborating with cross-functional teams allowed me to contribute to innovative drug candidate evaluations.

    • Research Scientist II
      May 2018 - Apr 2021 · 3 yrs

  • Visiting Graduate Student at Massachusetts Institute of Technology
    Sep 2019 - May 2021 · 1 yr 9 mos

    During my time at the Koch Institute for Integrated Cancer Research, I focused on self-amplifying RNA replicon technology, collaborating closely with Professor Darrell Irvine. This experience allowed me to enhance vaccine delivery methods and explore immunology applications, ultimately contributing to my Master's thesis on innovative cancer treatment strategies.

  • Harvard Extension School (Cambridge, MA)
    • Master of Liberal Arts Candidate
      Sep 2018 - May 2021 · 2 yrs 9 mos

      Thesis: Designing self-amplifying replicons for transient gene expression of interleukin-18 Thesis Director/Supervisor: Darrell Irvine

    • Faculty Aide
      Oct 2018 - Dec 2018 · 3 mos

      At Harvard Extension School, I contributed to research focused on mentoring, inclusion, and diversity in the sciences. Collaborating with faculty and students, I aimed to enhance the academic environment. My role involved analyzing data to uncover trends and best practices in science education, while honing my research methodologies and data analysis skills.

  • Research Support Associate at MIT Koch Institute for Integrative Cancer Research
    Mar 2017 - Apr 2018 · 1 yr 2 mos

    At the MIT Koch Institute for Integrative Cancer Research, I contributed to the advancement of vaccine technologies and immunotherapies. My role involved conducting laboratory experiments aimed at boosting immune responses against cancer. Working alongside a diverse team, I helped drive innovative research initiatives that are crucial for cancer treatment advancements.