Shirsha Saha

Postdoctoral Researcher | GPCR Signaling & Pharmacology | Decoding Orphan Receptors | PMRF Fellow

Darmstadt, Hesse, Germany

About

An enthusiastic researcher driven by a deep passion for scientific discovery, particularly in the realm of G protein-coupled receptors (GPCRs). My research is focused on the identification and characterization (molecular and structural) of ligands targeting these crucial signaling proteins, with the ultimate goal of contributing to advancements in drug discovery. I am currently working on the deorphanization of GPCRs. I hold a Ph.D. in Biological Sciences and Bioengineering with expertise in GPCR biochemistry, soluble and membrane protein purification, and in vitro pharmacological characterization. During my doctoral work, I spearheaded multiple projects that elucidated the structural and molecular basis of biased signaling in chemoattractant GPCRs.

Experience

  • Postdoctoral Researcher at Technische Universität Darmstadt
    May 2026 - Present · 3 mos

  • Postdoctoral Associate at University of Rochester
    Apr 2025 - Mar 2026 · 1 yr

  • Doctoral Student at Indian Institute of Technology, Kanpur
    Jul 2019 - Dec 2024 · 5 yrs 6 mos