Sergio Espeso Gil, PhD

Senior Scientist | Computational Oncology & AI

Barcelona, Catalonia, Spain

About

I earned my PhD in Biomedicine from Universitat Pompeu Fabra (Barcelona, 2016), where I mastered Bioinformatics and Next Generation Sequencing (NGS) technologies to uncover the complex mechanisms that govern gene regulation. My experimental research journey began with a passion for Neuroscience at Pierre et Marie Curie University in Paris through an Erasmus fellowship, followed by a Master’s in Neuroscience at the Autonomous University of Madrid, where I strengthened my computational and analytical expertise. During my PhD at the Center for Genomic Regulation (CRG) in Barcelona, I pioneered the integration of multiomics data to explore how gene regulation influences brain function during learning. Upon completion, I joined Mount Sinai Hospital in New York as a Postdoctoral Fellow, where I investigated the 3D genome architecture of the human brain and uncovered molecular mechanisms underlying psychiatric disorders. After a postdoctoral stage at the SickKids Research Institute in Toronto, I transitioned to industry as a Bioinformatics Consultant at Clarivate, leading projects in single-cell RNA-seq, spatial transcriptomics, PacBio IsoSeq, gene editing, and machine learning, providing tailored solutions to global clients. Currently, I serve as a Senior Scientist at AstraZeneca, leveraging my expertise at the intersection of data, biology, and innovation to advance precision oncology.

Experience

  • Senior Scientist at AstraZeneca
    Sep 2025 - Present · 11 mos

  • Clarivate (5 yrs)
    • Senior Bioinformatics Consultant
      Oct 2024 - Sep 2025 · 1 yr

    • Bioinformatics Consultant
      Nov 2022 - Sep 2024 · 1 yr 11 mos

    • Research Scientist. Bioinformatician
      Oct 2020 - Oct 2022 · 2 yrs 1 mo

  • Senior Scientist Collaborator at Medizinische Universität Innsbruck
    Apr 2021 - Dec 2023 · 2 yrs 9 mos

  • Postdoctoral Fellow at The Hospital for Sick Children
    Oct 2019 - Sep 2020 · 1 yr

  • Postdoctoral Fellow at Icahn School of Medicine at Mount Sinai
    May 2017 - Sep 2019 · 2 yrs 5 mos