Semih Tareen

Biotechnology Leadership, Gene and Cell Therapy

Greater Seattle Area

About

Advancing cell and gene therapies for patients with amazing teams and cutting edge science.

Experience

  • Consultant: Biotechnology Research & Development, Strategy & Leadership at Biotech
    Jan 2024 - Present · 2 yrs 6 mos

    Helping daring gene and cell therapy companies and institutions achieve their R&D and CMC milestones.

  • Sana Biotechnology, Inc. (4 yrs 11 mos)
    • Executive Director
      Sep 2022 - Oct 2023 · 1 yr 2 mos

      Head of Viral Vector Research. Lead a research team working on IND enabling and IND approved cell and gene therapies. Development of viral vectors for use as in vivo gene delivery therapies, overcoming intrinsic barriers to cell therapy gene delivery.

    • Senior Director
      Dec 2018 - Sep 2022 · 3 yrs 10 mos

      Head of Viral Vector Research. Building a team developing cell and gene therapies. Cancer Immunotherapy, Viral Vectors, Molecular Biology, Genetic Engineering, cell control.

  • Director at Juno Therapeutics, Inc.
    Jun 2014 - Dec 2018 · 4 yrs 7 mos

    Head of Gene Engineering & Delivery. Leading a research team developing CAR-T cell therapies, viral and non-viral vectors, molecular engineering, suicide switches. Part of the team that developed FDA approved CAR-T cell therapy, Breyanzi as well as other IND-approved cell therapies. Cancer Immunotherapy, Viral Vectors, Molecular Biology, Genetic Engineering, cell control.

  • Scientist II at Immune Design
    Jul 2010 - Jun 2014 · 4 yrs

    - Developed the ZVex (LV305) platform from pre-clinical to clinical stage. - Expertise in viral vectors, particularly lentiviral vector design, technology, manufacturing, and CMC. - Cancer Immunotherapy, particularly dendritic cell biology. - Virus and host interactions, particularly in considerations of viral vectors designed to successfully transduce host targets. - IND enabling preclinical studies. - IND, RAC, IB and other regulatory filings.

  • Graduate Research Assistant at Fred Hutchinson Cancer Research Center
    Sep 2005 - Jun 2010 · 4 yrs 10 mos

    PhD thesis on virus host interactions in the lab of Michael Emerman.