Sebastian W. Fuchs

Lab Head Bioassay Automation at Merck Healthcare, Darmstadt, Germany

Erlensee, Hesse, Germany

About

Lab Head in Bioassay automation for Hight Throughput Screening assays in the drug discovery process. Former project coordinator leading teams within a matrix organization for antibody release studies under GMP. Skilled in Liquid Chromatography- as well as MALDI-Mass Spectrometry, ADC-analytics, Biotechnology, MSD, and Quantitative Bioanalytics. Strong research experience with a Doctor of Philosophy from Goethe University Frankfurt and a Post-Doc at ETH Zurich - focused on Molecular Biotechnology and Mass Spectrometry-based analytics.

Experience

  • Merck Healthcare (Darmstadt, Hesse, Germany)
    • Lab Head Bioassay Automation
      Mar 2021 - Present · 5 yrs 4 mos

      - High Throughput Screening (HTS) for drug discovery - DMTA-cycle automation - Biochemical and cellular assays - Data analysis and hit triaging - Leading technology development projects in automation - Project management during HTS campaigns - Management of 4 FTEs including recruitment and development planning for employees

    • Lab Head High-Throughput Mass Spectrometry (interim)
      Sep 2023 - Mar 2024 · 7 mos

      Lab Head for High-Throughput Mass Spectrometry with a focus on Affinity Selection-Mass Spectrometry (AS-MS).

  • Merck KGaA, Darmstadt, Germany (Darmstadt, Hesse, Germany)
    • Senior Scientist Quantitative Bioanalysis
      May 2018 - Mar 2021 · 2 yrs 11 mos

      - Project coordination for antibody release studies under GMP/GLP - Quantitative Bioanalysis of APIs in biological matrices (MRM, (U)HPLC-MS/MS, MALDI-MS) - Quantitative Bioanalysis of therapeutic antibodies via MSD - Innovation Scouting - Method Scouting - Project Management

    • Scientist Quantitative Bioanalysis
      Jun 2017 - Apr 2018 · 11 mos

      - Quantitative Bioanalysis of APIs in biological matrices (MRM, (U)HPLC-MS/MS) - Method Scouting - Innovation Scouting - Team Leader during Merck KGaA´s Innospire Initiative

  • Postdoctoral Researcher at ETH Zurich
    Apr 2014 - Mar 2017 · 3 yrs

    - With Prof. Piel - Biosynthetic studies of post-translationally modified proteins - Mass spectrometry-based quantification & structure elucidation of modified protein species - Genetic in silico analyses - Genetic modification of biosynthetic machineries - Student supervisor

  • Scientific Associate at Goethe University
    Jun 2013 - Feb 2014 · 9 mos

    - With Prof. Bode - Whole Genome sequencing - MALDI-MS/MS - (U)HPLC-ESI-MS/MS - Molecular biology - Molecular biotechnology - Student supervisor