The Hague, South Holland, Netherlands
https://pomplunlab.com/
Development of combinatorial drug discovery platforms for novel chemical modalities Structure guided design of peptidomimetic therapeutics Synthetic transcription factors Bioorthogonal reaction development
Development of new bioorthogonal reactions (for Site Specific Conjugation on antibodies, proteins, condensation of biomolecules etc.). Design and synthesis of unnatural amino acids and phosphoramidites (building blocks, functional linkers, cleavable linker etc). Solid Phase Peptide and Oligonucleotide synthesis. Peptide-Oligonucleotide conjugates (POCs).
PhD Summa cum Laude Design and synthesis of small molecule inhibitors for FK506 binding proteins. Experience in : Drug Design and Modeling Organic Synthesis HPLC, LCMS, NMR eADME Protein - Ligand Affinity Assays