Leipzig, Saxony, Germany
Biochemist and Enzyme Engineer. My research experience is focused on structure and mechanism guided protein design, focused directed evolution, enzyme mechanism, computer modeling and bioinformatics. I have proficient knowledge in biocatalysis, micro- and molecular biology, biochemistry, protein purification and characterization, high-throughput screening techniques and molecular dynamic simulations. My recent research is based on protein design to optimize biocatalysts for industrial applications. Specialties: rational protein design, structure-function relationship, directed evolution, high-throughput screening, molecular dynamic simulations, molecular biology, biocatalysis, biotransformation, bioinformatics.
Protein Engineering, Protein Design, Directed Evolution, Bioinformatics Optimization of enzymes for industrial applications
Protein Engineering, Protein Design, Directed Evolution Optimization of enzymes for industrial application
Biocatalytic amination reactions using ammonia lyases and aminomutases; Protein design and molecular modelling; supervision of bachelor- and PhD-students
Optimization of enzymes for industrial applications.
Protein design of a phenylalanine ammonia lyase - Change of substrate spectrum and investigations about the mechanism; Participated in several other projects mainly based on directed evolution, protein desing and computer modelling
Internship in the group of Prof. Dr. Karl Hult, Department of Biotechnology at KTH, Stockholm, Sweden